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Search Results for " parathyroid hormone "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T73692	Parathyroid hormone
	Parathyroid hormone (PTH), an 84-amino acid circulating hormone synthesized in the parathyroid glands, primarily regulates bone and kidney functions to maintain extracellular calcium levels within normal ranges. It is al...
T21535	Parathyroid Hormone (1-34), bovine		Thyroid hormone receptor(THR)
	Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bovine is used to study osteoporosis and hypoparathyroidism.		Thyroid hormone receptor(THR)
T36767	Parathyroid Hormone (1-13) (trifluoroacetate salt)
	Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats.
TP1964	Parathyroid hormone (1-34) (rat)
	Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.
TP2283	parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]		Others
	parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid...		Others
T76084	Parathyroid Hormone (1-34), human, biotinylated
	Parathyroid Hormone (1-34), human, biotinylated serves as a probe targeting the parathyroid hormone receptor. It is utilized in the analysis of interactions between parathyroid hormone and its receptors within living cel...
T76061	Parathyroid hormone (1-34) (rat) acetate
	Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone variant that enhances the structure of both cortical and cancellous bones. It is utilized in osteoporosis research [1] [2].
T75867	Parathyroid Hormone (1-34), bovine TFA
	Parathyroid Hormone (1-34), bovine TFA, a potent agonist of the parathyroid hormone (PTH) receptor, elevates calcium and inorganic phosphate levels in vivo. This compound is employed in osteoporosis research [1].
T21460	Teriparatide acetate	hPTH 1-34 (acetate salt),Parathar acetate,Forteo	Others
	Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat...		Others
T13128	Teriparatide	Human parathyroid hormone-(1-34),hPTH (1-34),PTH 1-34	Others
	Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).		Others
T2406	Cinacalcet hydrochloride	AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet	CaSR
	Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces para...		CaSR
T16015	Maxacalcitol	22-Oxacalcitriol	Others
	Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.		Others
TP1215L	Abaloparatide acetate(247062-33-5 free base)		Others
	Abaloparatide acetate is a parathyroid hormone receptor 1 PTHR1 analogue and an effective and selective activator of the PTHR1 signaling pathway.		Others
TP1215	Abaloparatide TFA	BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA	Others
	Abaloparatide TFA (BIM 44058 TFA) is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis like the related drug teriparatide.		Others
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate		Thyroid hormone receptor(THR)
	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane.		Thyroid hormone receptor(THR)
T29067	Upacicalcet	PLS-240,SK-1403,AJT-240	Calcium Channel
	Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s...		Calcium Channel
TP1236	Etelcalcetide hydrochloride	AMG 416 hydrochloride,KAI-4169 hydrochloride	CaSR
	Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi...		CaSR
T29067L	Upacicalcet HCl	Upacicalcet HCl(1333218-50-0 Free base)	CaSR
	Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ...		CaSR
TP1906L1	DPC AJ1951 acetate		Thyroid hormone receptor(THR)
	DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 acetate in ex vivo and in vivo a...		Thyroid hormone receptor(THR)
T10665	Calcium-Sensing Receptor Antagonists I		Others
	Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.		Others
T36919	1α-Hydroxy-3-epi-vitamin D3	1α-Hydroxy-3-epi-vitamin D3
	1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].
T39444	Upacicalcet sodium
	Upacicalcet (sodium) is an intravenous calcimimetic agent that acts directly on parathyroid cell membrane calcium-sensing receptors to suppress excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH le...
TP1906	DPC-AJ1951	DPC AJ1951
	Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).
T61232	(Rac)-Upacicalcet
	(Rac)-Upacicalcet is a racemate of Upacicalcet, which serves as an intravenous calcimimetic agent. Upacicalcet acts by directly targeting calcium-sensing receptors on parathyroid cell membranes, effectively suppressing t...
T77991	Glutaurine TFA	Litoralon TFA
	Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in...
TP1688	TIP 39, Tuberoinfundibular Neuropeptide
	This is a tuberoinfundibular neuropeptide and parathyroid hormone 2(PTH 2)-receptor agonist from hypothalmus. Synthetic TIP39 activates human and rat PTH2 receptors.
T25455L	Glutaurine aceate		Thyroid hormone receptor(THR)
	Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine aceate, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine aceate can be used...		Thyroid hormone receptor(THR)
T25234	CH5447240	CH 5447240,CH-5447240
	CH5447240 is an effective Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist for the treatment of Hypoparathyroidism. CH5447240 showed a potent in vitro hPTHR1 agonist effect (EC20: 3.0 nM; EC50: 12 nM). It showed 55%...
T76636	(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
	'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'
T81349	PTH-Related Protein (7-34) amide (human, mouse, rat)
	PTH-Related Protein (7-34) amide (human, mouse, rat) serves as a potent antagonist of parathyroid hormone (PTH) [1].
T12363	Paricalcitol-D6		Others
	Paricalcitol-D6 is the deuterated form of Paricalcitol, which is used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.		Others
T75272	Paricalcitol-d
	Paricalcitol-d6, a deuterium-labeled version of Paricalcitol, serves as a therapeutic agent for preventing and treating secondary hyperparathyroidism (excessive secretion of parathyroid hormone) linked to chronic renal f...
T35500	3-epi-25-hydroxy Vitamin D3	3-epi-25-hydroxy Vitamin D3
	3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, we...
T81350	PTH-Related Protein (1-37) (human, mouse, rat)
	PTH-Related Protein (1-37) (human, mouse, rat) is a peptide analog of parathyroid-hormone-related protein (pTHrP), which plays a role in the physiological regulation of bone formation [1].
T35524	(1S)-Calcitriol
	(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3), a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), exerts potent actions through vitamin D receptor (VDR) activation, including the inhibition of keratin...
T81591	Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)	Human PTHrP(107-111) amide
	Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroid hormone-related protein that inhibits bone resorption [1] [2].
T76649	Osteostatin (human)
	Osteostatin (human), a fragment derived from parathyroid hormone-related protein (PTHrP) 107-139, effectively promotes bone repair in animal models with bone defects and inhibits bone erosion in cases of inflammatory art...
T75942	DPC-AJ1951 TFA
	DPC-AJ1951 TFA, a 14-amino acid peptide, functions as a potent agonist for the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). It has been characterized for its activity through ex vivo and in vivo bone res...
T73132	DS69910557
	DS69910557, a potent, selective, and orally active antagonist of the human parathyroid hormone receptor 1 (hPTHR1), exhibits antagonistic activity with an IC50 value of 0.08 μM. It is useful in researching hyperparathyro...
T77990	Human PTHrP-(1-36)
	Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function and proliferation. It is utilized in research pertaining to humoral hyperca...
T73690	Abaloparatide
	Abaloparatide (BA 058), a parathyroid hormone receptor 1 (PTHR1) analog and selective activator, promotes Gs/cAMP signaling and β-arrestin recruitment, thereby enhancing bone formation and improving cortical structure in...
T37409	DPC-AJ1951 (trifluoroacetate salt)	DPC-AJ1951 (trifluoroacetate salt)
	DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogen...
T83178	ACTH (6-24) (human)	Adrenocorticotropic hormone (6-24)
	Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human)) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-length ACTH (1-39) and the shortened ACTH (5-24), with dissociation ...
T76660	PTH (1-37) (human)
	pTH (1-37) (human), a fragment of parathyroid hormone (PTH), promotes cAMP formation and enhances alkaline phosphatase activity. Additionally, it fosters growth, elevates bone calcium content, and augments bone mineral d...
T36385	Ansatrienin A
	Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM)...
T76657	Human PTH-(1-31)
	Human PTH-(1-31), the 1-31 fragment of human parathyroid hormone, stimulates cAMP release and mildly activates 25-hydroxyvitamin D-1α-hydroxylase. Unlike its full-length counterpart, it promotes bone formation without tr...
T81592	Osteostatin	PTHrP (107–111)
	Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e...
T36650	Ansatrienin B
	Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM...
T76663	PTH-Related Protein (1-40) (human, mouse, rat)
	pTH-Related Protein (1-40) (human, mouse, rat) enhances calcium absorption in rat intestinal cells by activating the PTHR1 receptor and the PKCα/β signaling pathways. This compound also increases the expression of the pa...
T83733	TIP39 (human, bovine) TFA	Tuberoinfundibular Peptide of 39 Residues
	TIP39, a neuropeptide and an agonist for the parathyroid hormone receptor type 2 (PTH2R), effectively increases cAMP levels in COS-7 cells featuring recombinant PTH2R from humans or rats (EC50s = 0.5 and 0.8 nM, respecti...

Compounds

Parathyroid hormone

T73692

Synonym:

Target:

Parathyroid Hormone (1-34), bovine

T21535

Synonym:

Target: Thyroid hormone receptor(THR)

Parathyroid Hormone (1-13) (trifluoroacetate salt)

T36767

Synonym:

Target:

Parathyroid hormone (1-34) (rat)

TP1964

Synonym:

Target:

parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]

TP2283

Synonym:

Target: Others

Parathyroid Hormone (1-34), human, biotinylated

T76084

Synonym:

Target:

Parathyroid hormone (1-34) (rat) acetate

T76061

Synonym:

Target:

Parathyroid Hormone (1-34), bovine TFA

Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo

Target: Others

Teriparatide

T13128

Synonym: Human parathyroid hormone-(1-34),hPTH (1-34),PTH 1-34

Target: Others

Cinacalcet hydrochloride

T2406

Synonym: AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet

Target: CaSR

Maxacalcitol

T16015

Synonym: 22-Oxacalcitriol

Target: Others

Abaloparatide acetate(247062-33-5 free base)

Synonym: BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA

Target: Others

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate

T9691L

Synonym:

Target: Thyroid hormone receptor(THR)

Upacicalcet

T29067

Synonym: PLS-240,SK-1403,AJT-240

Target: Calcium Channel

Etelcalcetide hydrochloride

TP1236

Synonym: AMG 416 hydrochloride,KAI-4169 hydrochloride

Target: CaSR

Upacicalcet HCl

T29067L

Synonym: Upacicalcet HCl(1333218-50-0 Free base)

Target: Thyroid hormone receptor(THR)

Calcium-Sensing Receptor Antagonists I

T10665

Synonym:

Target: Others

1α-Hydroxy-3-epi-vitamin D3

T36919

Synonym: 1α-Hydroxy-3-epi-vitamin D3

Synonym: Litoralon TFA

Target:

TIP 39, Tuberoinfundibular Neuropeptide

Target: Thyroid hormone receptor(THR)

CH5447240

T25234

Synonym: CH 5447240,CH-5447240

3-epi-25-hydroxy Vitamin D3

T35500

Synonym: 3-epi-25-hydroxy Vitamin D3

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)

T81591

Synonym: Human PTHrP(107-111) amide

DPC-AJ1951 (trifluoroacetate salt)

T37409

Synonym: DPC-AJ1951 (trifluoroacetate salt)

Target:

ACTH (6-24) (human)

T83178

Synonym: Adrenocorticotropic hormone (6-24)

Synonym: PTHrP (107–111)

TIP39 (human, bovine) TFA

T83733

Synonym: Tuberoinfundibular Peptide of 39 Residues

Target:

Cat No.	Product Name	Synonyms	Targets
T6316	Calcitriol	Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3	Endogenous Metabolite
	Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption...		Endogenous Metabolite
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)

Natural Products

Calcitriol

T6316

Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3

Target: Endogenous Metabolite

PCO371

T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00740	PTH Protein, Human, Recombinant	Human	E. coli
	Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells...
TMPY-03191	PTH Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	PTH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.9 kDa and the accession number is P01270.
TMPJ-00741	PTH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This ho...
TMPY-02764	PTH Protein, Human, Recombinant (aa 32-65, GST)	Human	E. coli
	PTH Protein, Human, Recombinant (aa 32-65, GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 31 kDa and the accession number is P01270.
TMPY-02236	PTH1R Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Parathyroid hormone / parathyroid hormone-related peptide receptor, also known as PTH / PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R and PTHR, is a multi-pass membrane pr...
TMPH-01528	IHH Protein, Human, Recombinant (His)	Human	E. coli
	Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target gen...
TMPJ-00253	OPG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulat...